English translation for "tyrosine phosphorylation"
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- 酪氨酸磷酸化
Related Translations:
- Example Sentences:
| 1. | Focal adhesion kinase tyrosine phosphorylation promotes rat hepatic fibrogenesis and its possible mechanism
黏着斑激酶酪氨酸磷酸化促大鼠肝纤维化形成及其可能机制 | | 2. | Effects of free fatty acid on gene expression and protein tyrosine phosphorylation of leptin - receptor in rats
游离脂肪酸对大鼠瘦素受体基因表达及蛋白酪氨酸磷酸化的影响 | | 3. | The purposes of this study were to investigate the possible effects of exposure to 50hz mf on protein tyrosine phosphorylation , sapk signal pathway and p38 mapk signal pathway
所以本实验以蛋白质酪氨酸磷酸化为起点，研究极低频磁场对sapk途径及p38mapk途径的影响。 | | 4. | Effects of 50hz magnetic field on protein tyrosine phosphorylation in cultured cells protein cascade phosphorylation is one of the main modes of signal transduction pathway and protein activation in cells
4mt强度还可使61 7 、 105及112kda的蛋白质酪氨酸磷酸化发生改变，而0 smt强度却使79 、 150kda的蛋白质酪氨酸磷酸化发生变化。 | | 5. | We also found that p1206 " 1 can be easily phosphorylated at tyrosine by epidermal growth factor ( egf ) . tyrosine phosphorylation of p ! 20ctn strengthened bel - 7404 cells malignant behavior , and p120ctn translocated into nucleus
我们还发现，芒果贰有降低pi20ctn磷酸化的作用，其结果是bel一7404细胞粘附能力有所增强，迁移能力降低。 | | 6. | Spla 2 can significantly inhibits egf - induced egf receptorautophosphorylation , which also resulted in the inhibitionon egf - induced phospholipase d activation and tyrosine phosphorylation of phospholipase c - g 1 . under the same condition , spla 2 can induce intracellular ceramidegeneration . moreover , exogenous ceramide analogs can also significantly inhibit such biologicalevent induced by egf , suggesting that ceramide may play an important role in spla 2 - induced cell death and the signaling events
在相同的条件下，分泌型磷脂酶a亦能诱导细胞内神经酰胺生2成的增加；外源性的神经酰胺类似物也能有效的抑制表皮生长因子诱导的这些生物事件，提示神经酰胺在分泌型磷脂酶a所介导的细胞死亡和信号传导事件2中起着重要的作用。 | | 7. | It has been demonstrated that kvl . 2 , an isoform of delayed - rectifier potassium channel , is up - regulated in the ischemic neurons . besides , the activity of kvl . 2 is tyrosine phosphorylation dependent , phosphorylation of the tyrosine residue in the amino terminus of the channel by tyrosine kinases suppresses the channel current . therefore , we hypothesize that vegf could enhance the phosphorylation of kvl . 2 , which results in an inhibition of / k
在介导i _ k的钾通道家族中， kv1 . 2是其中的一个亚型，研究报道它在缺血神经元中的表达是增高的；此外，它的活性与其酪氨酸磷酸化水平相关，在其氨基末端的酪氨酸残基经酪氨酸激酶磷酸化后可显著降低其介导的电流的幅度。 | | 8. | To make clear the hypothesis , a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study , respectively . we first studied the cellular localization of kvl . 2 and the co - localization of kvl . 2 protein and vegf receptors flk - 1 and flt - 1 , observed the effect of mcao on kvl . 2 expression and phosphrylation in the rat brain in vivo , then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl . 2 in sh - sy5y cells . finally , in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl . 2 phosphorylation , we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl . 2 phosphorylation
为了验证上述假设，本文分别在整体和离体水平，采用大脑中动脉缺血( middlecerebralarteryocclusion ， mcao )和体外氧?糖剥夺( hypoxiaandglucose - deprivation ， hgd )缺血模型，首先了解了kv1 . 2蛋白的细胞定位及与vegf受体flk - 1和flt - 1的共存情况，观察了整体mcao后缺血再灌不同时间大鼠脑内kv1 . 2蛋白的磷酸化水平变化，然后通过外源性给予vegf蛋白，在sh - sy5y细胞株上观察其对缺血细胞存活率及kv1 . 2蛋白磷酸化水平的影响，最后利用vegf反义脱氧寡核苷酸( oligodeoxynucleotide ， odn )特异阻断内源性vegf蛋白的表达，观察内源性vegf蛋白在缺血细胞损伤及调节kv1 . 2蛋白磷酸化中的作用，以进一步明确vegf缺血保护效应与其调节kv1 . 2蛋白磷酸化之间的关系。 |
- Similar Words：
- "tyrosine methyl ester" English translation, "tyrosine oxidase" English translation, "tyrosine phenol-lyase" English translation, "tyrosine phosphatase" English translation, "tyrosine phosphorylated protein" English translation, "tyrosine protein kinase" English translation, "tyrosine protein kinase tpk" English translation, "tyrosine protein kinase,tpk" English translation, "tyrosine side chain" English translation, "tyrosine sulfation" English translation
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